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With the growing demand for digital information in health care, the electronic medical record (EMR) represents the foundation of health information technology. It is essential, however, in an industry still largely dominated by paper-based records, that such systems be accepted and used. This research evaluates registered nurses’, certified nurse practitioners and physician assistants’ acceptance of EMR’s as a means to predict, define and enhance use. The research utilizes the Unified Theory of Acceptance and Use of Technology (UTAUT) as the theoretical model, along with the Partial Least Square (PLS) analysis to estimate the variance. Overall, the findings indicate that UTAUT is able to provide a reasonable assessment of health care professionals’ acceptance of EMR’s with social influence a significant determinant of intention and use.