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In today’s global economy, there is a growing need to apply technological advancements as well as training and awareness materials from western countries on information security programs in developing nations. To understand the underlying drivers of employees’ effective use behaviors in relation to security awareness programs in organizations, this study examines the extrinsic and intrinsic motivation factors that influence employees located in developing nations. The results indicate that influencing employees’ attitudes toward security is a better predictor of employees’ effective use of security awareness programs than their intention to comply. Cultural effects has also proven to have an influence on employees’ effective use of security awareness programs.